Indications: AN AMIDE LOCAL ANESTHETIC CONTAINING A VASOCONSTRICTOR IS INDICATED FOR LOCAL INFILTRATIVE OR CONDUCTIVE ANESTHESIA IN BOTH SIMPLE AND ,COMPLEX DENTAL PROCEDURES , SOLUTION FOR DENTAL INJECTION, ARTICAINE HCL IS AN AMIDE LOCAL ANESTHETIC , LOCAL ANESTHETICS BLOCK THE GENERATION AND CONDUCTION OF NERVE IMPULSES PRESUMABLY BY INCREASING THE THRESHOLD FOR ELECTRICAL EXCITATION IN THE NERVE BY SLOWING THE PROPAGATION OF THE NERVE IMPULSE AND BY REDUCING THE RATE OF RISE OF THE ACTION POTENTIAL. IN GENERAL THE PROGRESSION OF ANESTHESIA IS RELATED TO THE DIAMETER MYELINATION AND CONDUCTION VELOCITY OF THE AFFECTED NERVE FIBERS EPINEPHRINE IS A VASOCONSTRICTOR. ADDED TO ARTICAINE HCL TO SLOW ABSORPTION INTO THE GENERAL CIRCULATION AND THUS PROLONG MAINTENANCE OF AN ACTIVE TISSUE CONCENTRATION